rs396991
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We genotyped FcγRIIIa-158V/F (rs396991) using a pyro-sequencing assay (PSQ 96MA) in a total of 732 individuals with SLE (390 lupus nephritis and 342 non-lupus nephritis) and 886 controls.
|
24131500 |
2013 |
rs11981433
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found no association of PON2 SNPs with SLE risk but modest associations were observed with lupus nephritis (rs11981433, rs17876205, rs17876183) and immunologic disorder (rs11981433) in SLE patients (P = 0.013 to 0.042).
|
21223581 |
2011 |
rs114580964
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We discovered five independent risk variants for LN within the MHC region, including <i>HLA-DRβ1</i> amino acid 11 (<i>P</i><sub>omnibus</sub><0.001), <i>HLA-DQβ1</i> amino acid 45 (<i>P</i><0.001; odds ratio, 0.58; 95% confidence interval, 0.52 to 0.65), <i>HLA-A</i> amino acid 156 (<i>P</i><sub>omnibus</sub><0.001), <i>HLA-DPβ1</i> amino acid 76 (<i>P</i><sub>omnibus</sub><0.001), and a missense variant in <i>PRRC2A</i> (rs114580964; <i>P</i><0.001; odds ratio, 0.38; 95% confidence interval, 0.30 to 0.49) at genome-wide significance.
|
28754791 |
2017 |
rs3746444
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This is the first report documenting that the <i>miR-146a</i> rs2910164G/C and <i>miR-499</i> rs3746444 polymorphisms are associated with SLE susceptibility but not with LN.
|
29190882 |
2017 |
rs2910164
|
|
|
0.020 |
GeneticVariation |
BEFREE |
This is the first report documenting that the <i>miR-146a</i> rs2910164G/C and <i>miR-499</i> rs3746444 polymorphisms are associated with SLE susceptibility but not with LN.
|
29190882 |
2017 |
rs172378
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These results support the implication of the G allele in rs172378 as a risk factor for lupus nephritis in a homozygous status, at least for a Bulgarian population.
|
25326229 |
2015 |
rs1061170
|
|
|
0.010 |
GeneticVariation |
BEFREE |
There was a significantly higher ratio of CC/CT genotypes of rs1061170 in lupus nephritis patients with class III than in the other two classes (class III vs. class IV vs. class V: 21.0% vs. 9.7% vs. 9.4%; P = .044).
|
28403670 |
2017 |
rs1267969615
|
|
|
0.010 |
GeneticVariation |
BEFREE |
There was no association between genetic polymorphism of ACE, AGT M235T and AGTR1 A1166C and susceptibility to lupus nephritis, nor histological activity and chronicity indices in renal biopsy among the patients studied.
|
16047641 |
2005 |
rs699
|
|
|
0.010 |
GeneticVariation |
BEFREE |
There was no association between genetic polymorphism of ACE, AGT M235T and AGTR1 A1166C and susceptibility to lupus nephritis, nor histological activity and chronicity indices in renal biopsy among the patients studied.
|
16047641 |
2005 |
rs8091180
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The SNP rs8091180 in NFATC1 was associated with LN (OR 1.43, p = 3.3E-04) in the candidate SNP meta-analysis with the highest OR among African-Americans (OR 2.17, p = 0.0035).
|
29953444 |
2018 |
rs800292
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs6677604-GG genotype was observed to be associated with the absence of anti-ds DNA antibody ( P = .021), and the rs800292-TT genotype was associated with a higher level of circulating C3 ( P = 0.20) in lupus nephritis.
|
28403670 |
2017 |
rs2004640
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The results suggested that the rs2004640 T allele was associated with susceptibility to lupus nephritis and that the IRF5 polymorphism analyzed did not seem to be implicated in the pathology and clinical manifestation of lupus nephritis in the Chinese population.
|
21040166 |
2010 |
rs28940579
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The prevalence of four MEFV gene mutations (M694V, M680I, V726A and E148Q) was investigated in 114 SLE patients and effect on disease severity was analyzed in patients with biopsy-proven SLE nephritis.
|
25413357 |
2015 |
rs2910164
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The objective of this study was to identify the association between genotypes of miR-146a rs2910164 and expression of TRAF6 as well as the risk of lupus nephritis (LN).
|
29754557 |
2017 |
rs10127939
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The low-binding haplotypes formed by 66L/R/H and 176F confer enhanced risk of lupus nephritis in African Americans.
|
24782186 |
2014 |
rs8193037
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of this study was to investigate whether the IL-17A -737 T/C (rs8193036), -444A/G (rs3819024), -197G/A (rs2275913), and -121G/A (rs8193037) SNPs conferred susceptibility to SLE (or lupus nephritis) or to RA in a Mexican population.
|
30398030 |
2019 |
rs292001
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The A allele and AA genotype of C1q rs292001 can be considered a susceptibility risk factor and the GG genotype could be considered protective for jSLE and LN in the studied cohort of Egyptian children.
|
26095468 |
2015 |
rs6677604
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs6677604-GG genotype was observed to be associated with the absence of anti-ds DNA antibody ( P = .021), and the rs800292-TT genotype was associated with a higher level of circulating C3 ( P = 0.20) in lupus nephritis.
|
28403670 |
2017 |
rs2295415
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SNP rs2295415 appears to confer higher risk to develop anti-Sm antibodies-positive SLE and may play a protective role against lupus nephritis.
|
26601115 |
2015 |
rs11057864
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Response to Intravenous Cyclophosphamide Treatment for Lupus Nephritis Associated with Polymorphisms in the FCGR2B-FCRLA Locus.
|
26980576 |
2016 |
rs1108131
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Response to Intravenous Cyclophosphamide Treatment for Lupus Nephritis Associated with Polymorphisms in the FCGR2B-FCRLA Locus.
|
26980576 |
2016 |
rs6697139
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Response to Intravenous Cyclophosphamide Treatment for Lupus Nephritis Associated with Polymorphisms in the FCGR2B-FCRLA Locus.
|
26980576 |
2016 |
rs7692514
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Response to Intravenous Cyclophosphamide Treatment for Lupus Nephritis Associated with Polymorphisms in the FCGR2B-FCRLA Locus.
|
26980576 |
2016 |
rs958476
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Response to Intravenous Cyclophosphamide Treatment for Lupus Nephritis Associated with Polymorphisms in the FCGR2B-FCRLA Locus.
|
26980576 |
2016 |
rs3792192
|
|
|
0.010 |
GeneticVariation |
BEFREE |
PLA2R1 displayed a nominally significantly genetic association with SLE [for rs4664308, P = 0.02, odds ratio (OR) 1.16, 95 % confidence interval (CI) 1.02-1.31; for rs3792192, P = 7.9 × 10(-3), OR 1.18, 95 % CI 1.05-1.34] and LN (for rs4664308, P = 0.04).
|
26645973 |
2016 |